About

The Paul and Diane Manning Institute of Biotechnology

The University of Virginia Paul and Diane Manning Institute of Biotechnology is being built to transform scientific discovery into medicine at unprecedented speed. Anchored in UVA's history of innovation in cell, gene and immunotherapies, the institute unites world-class scientists, clinicians, and entrepreneurs to develop treatments for the world's most devastating diseases. With innovative funding models, a cutting-edge facility, and a relentless focus on moving breakthroughs from lab to bedside, we accelerate the creation of new medicines, new partnerships, and new companies. In doing so, we will create an unparalleled life sciences ecosystem that will serve as a powerful economic engine for Virginia and position UVA as a global leader in biomedical innovation, delivering real hope and real treatments faster than ever before—because patients are waiting. 

Our Mission 

We accelerate the transformation of breakthrough science into life-saving medicines by dismantling the traditional barriers between discovery and clinical impact. Through strategic collaboration across disciplines and sectors, we compress the timeline from innovation to patient care.

Our Approach 

The Manning Institute operates at the intersection of academic excellence and entrepreneurial agility. We bring together UVA's leading researchers with industry partners, venture capital, and clinical experts to create a seamless pathway from laboratory discovery to FDA-approved treatments. Our unique funding structure and state-of-the-art infrastructure enable rapid iteration, bold experimentation, and swift translation of promising therapies into clinical trials. 

Our Impact 

By fostering an ecosystem where innovation thrives, we're not only advancing medicine—we're building Virginia's biotech future, creating jobs, attracting investment, training the next generation of leaders, and establishing the Commonwealth as a destination for life sciences innovation with global impact. 

Donors

Paul and Diane Manning

Paul Manning, an entrepreneur with 30 years of experience in the health care industry, founded PBM Capital in 2010. In 1997, he founded PBM Products, which became the largest private label producer of infant formula and baby/toddler food in the world. Manning is an active member of the UVA community, having served on the UVA Strategic Planning Committee, the UVA Health Foundation, the President’s Advisory Committee, and the Honor the Future Campaign Executive Committee. Manning was named Virginia Entrepreneur of the Year by Ernst and Young in 2002. The Manning family has been a longtime supporter of UVA and UVA Health's research efforts.

Paul and Diane Manning